She is described as a prophetess, the daughter of Phanuel, from the tribe of Asher. Anna is notable for her devoutness and dedication to worship; she spent her days and nights at the temple, fasting and praying. Her story is situated within the context of the presentation of Jesus at the temple.

When Mary and Joseph bring the infant Jesus to the temple in Jerusalem to perform the rites required by the Law of Moses, Anna is present. Upon seeing Jesus, she gives thanks to God and speaks about the child to all who were looking forward to the redemption of Jerusalem. Anna's recognition of Jesus as the promised Messiah, even as an infant, underscores her spiritual insight and faithful anticipation of God's salvation.

Though her appearance in the Bible is brief, Anna's story is significant as it highlights themes of faithfulness, prophecy, and the recognition of Jesus as the Messiah. Her presence in the narrative complements that of Simeon, another devout figure who also recognizes Jesus during the same visit to the temple. Together, they represent the faithful remnant of Israel awaiting the fulfillment of God's promises.